An update on the compound challenge: 4045-24-3

Although many compounds look similar to this compound(4045-24-3)Name: 4-Methoxypiperidine, numerous studies have shown that this compound(SMILES:COC1CCNCC1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Name: 4-Methoxypiperidine. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 4-Methoxypiperidine, is researched, Molecular C6H13NO, CAS is 4045-24-3, about Copper-Catalyzed ortho-Selective Dearomative C-N Coupling of Simple Phenols with O-Benzoylhydroxylamines. Author is Yao, Zhi-Li; Wang, Lei; Shao, Nan-Qi; Guo, Yin-Long; Wang, Dong-Hui.

In the presence of Cu(OTf)2 and LiOt-Bu in THF, 2,6-disubstituted phenols such as 2,6-dimethylphenol underwent regioselective dearomative coupling reactions with secondary O-benzoylhydroxylamines such as 4-(benzoyloxy)morpholine to yield aminocyclohexadienones such as I. Lack of inhibition with radical trapping agents, lack of rearrangement with a cyclopropylated phenol, and mass spectrometric detection of intermediates in the reaction support a mechanism involving either a single-electron transfer process involving attack of an N-centered radical onto the phenol or a two-electron pathway involving addition of phenol to an electrophilic Cu(III)-amino complex via an inner-sphere process.

Although many compounds look similar to this compound(4045-24-3)Name: 4-Methoxypiperidine, numerous studies have shown that this compound(SMILES:COC1CCNCC1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem