Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Research Support, Non-U.S. Gov’t, ChemSusChem called Chemoselective CaO-Mediated Acylation of Alcohols and Amines in 2-Methyltetrahydrofuran, Author is Pace, Vittorio; Hoyos, Pilar; Alcantara, Andres R.; Holzer, Wolfgang, which mentions a compound: 58081-05-3, SMILESS is O=C1OC[C@H](O)C1, Molecular C4H6O3, Recommanded Product: (R)-4-Hydroxydihydrofuran-2(3H)-one.
Calcium oxide is proposed as an innocuous acid scavenger for the chemoselective synthesis of amide- and ester-type compounds Although these mols. have wide spread applications in organic and pharmaceutical chem., and a large number of routes have been designed for their synthesis, the development of more efficient and environmentally friendly acylation strategies remains an ongoing challenge. The use of CaO allows for the stoichiometric acylation of primary alcs. in the presence of phenols or tertiary alcs.; amines can also be subjected to acylation reactions in the presence of hydroxyl groups. Chirality is obtained through acylation if the starting material is an optically pure alc. or if a chiral acylating agent is used. Furthermore, the use of 2-methyltetrahydrofuran (2-MeTHF), a more ecofriendly solvent, leads to maximized yields. This protocol is successfully applied to the synthesis of an interesting N-aryloxazolidin-2-one intermediate for the preparation of linezolid-type compounds
Although many compounds look similar to this compound(58081-05-3)Recommanded Product: (R)-4-Hydroxydihydrofuran-2(3H)-one, numerous studies have shown that this compound(SMILES:O=C1OC[C@H](O)C1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem