In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Preparative-Scale Synthesis of Vedejs Chiral DMAP Catalysts, published in 2018-10-19, which mentions a compound: 34941-92-9, mainly applied to scalable synthesis chiral Vedejs type DMAP catalyst; amination pyridine zinc amine complex; mechanistic study zinc facilitated nucleophilic aromatic substitution, Recommanded Product: 34941-92-9.
A scalable synthesis of chiral Vedejs-type DMAP catalysts is reported. The key step of the synthesis is amination of the enantiomerically pure 4-chloropyridine derivative using well-defined ZnCl2(amine)2 complexes. A series of Zn(II)-amine complexes have been synthesized to explore the scope of the ZnCl2-mediated amination of 4-halopyridines. Mechanistic studies support a Zn(II)-facilitated nucleophilic aromatic substitution as a plausible mechanism for the chlorine-to-amine exchange.
Although many compounds look similar to this compound(34941-92-9)Recommanded Product: 34941-92-9, numerous studies have shown that this compound(SMILES:ClC1=CC(=NC=C1)F), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem