In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called An acid-catalyzed 1,4-addition isocyanide-based multicomponent reaction in neat water, published in 2020, which mentions a compound: 4045-24-3, mainly applied to amine isocyanide chromone carboxaldehyde formic acid Ugi type addition; alkylaminomethylene oxochromane carboxamide preparation diastereoselective chemoselective green chem, Category: pyrrolines.
A green 1,4-addition isocyanide-based three-component reaction was developed to synthesize chromanones via a facile, mild, and efficient one-pot protocol without a metal catalyst. The 1,4-addition of isocyanides occurred at the C-2 position of chromones instead of the Schiff base in neat water. The hydrogen bond can dictate the stereo-outcome of olefins and provided an effective method for the diastereomer-selective synthesis of this type of chromanone. The novel green synthetic protocol allowed the quick synthesis of complex chromanones in an environmentally friendly manner.
Different reactions of this compound(4-Methoxypiperidine)Category: pyrrolines require different conditions, so the reaction conditions are very important.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem