Application of 136663-38-2

The article 《Design, synthesis and antimicrobial activity of novel 2-substituted benzoxazole derivatives》 also mentions many details about this compound(136663-38-2)SDS of cas: 136663-38-2, you can pay attention to it, because details determine success or failure

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: (2-Methylbenzo[d]oxazol-5-yl)methanol, is researched, Molecular C9H9NO2, CAS is 136663-38-2, about Design, synthesis and antimicrobial activity of novel 2-substituted benzoxazole derivatives.SDS of cas: 136663-38-2.

In the current research work, the title compounds were synthesized from Me 2-substituted benzoxazole-5-carboxylate by refluxing with methanol and THF (1 : 1) in presence of NaBH4, which afforded (2-substituted benzoxazol-5-yl)methanol, on partial oxidation with PCC furnished 2-substituted benzoxazole-5-carbaldehyde, on treatment with appropriate carbonyl compounds monoethyl malonate, Et acetoacetate or malonic acid yielded the corresponding α,β-unsaturated derivatives of 2-substituted benzoxazoles like, Et 3-(2-substituted benzoxazol-5-yl)acrylate, 4-(2-substituted benzoxazol-5-yl)but-3-en-2-one and 3-(2-substituted benzoxazol-5-yl)acrylic acid. The identification and characterization of all the synthesized compounds were confirmed by elemental anal., m.p., thin layer chromatog., FTIR, 1H NMR and mass spectral data. All the compounds were screened for antimicrobial activity. In view of interesting biol. activities and pharmacol. importance associated with benzoxazole derivatives, some of the derivatives of benzoxazole containing heterocyclic ring were prepared and their bio-potential were evaluated.

The article 《Design, synthesis and antimicrobial activity of novel 2-substituted benzoxazole derivatives》 also mentions many details about this compound(136663-38-2)SDS of cas: 136663-38-2, you can pay attention to it, because details determine success or failure

Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem