So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Mercado-Marin, Eduardo V.; Chheda, Pratik Rajesh; Faulkner, Andrea; Carrera, Diane researched the compound: (R)-4-Hydroxydihydrofuran-2(3H)-one( cas:58081-05-3 ).Recommanded Product: 58081-05-3.They published the article 《Magnesium ethoxide mediated lactone aminolysis with aminoheterocycles》 about this compound( cas:58081-05-3 ) in Tetrahedron Letters. Keywords: aromatic amine lactone aminolysis reaction; amino amide preparation. We’ll tell you more about this compound (cas:58081-05-3).
A mild method for the aminolysis of lactones with aminoheterocycles in the presence of magnesium ethoxide was described. A wide range of electronically diverse aminoheterocycles and substituted lactones successfully participated in this transformation to furnish the resulting amido-alc. products. Further application of this method to the synthesis of chiral α-amino amides derivatives was also described.
Different reactions of this compound((R)-4-Hydroxydihydrofuran-2(3H)-one)Recommanded Product: 58081-05-3 require different conditions, so the reaction conditions are very important.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem