So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Han, Dongyang; Li, Sasa; Xia, Siqi; Su, Mincong; Jin, Jian researched the compound: 4-Methoxypiperidine( cas:4045-24-3 ).Recommanded Product: 4045-24-3.They published the article 《Nickel-Catalyzed Amination of (Hetero)aryl Halides Facilitated by a Catalytic Pyridinium Additive》 about this compound( cas:4045-24-3 ) in Chemistry – A European Journal. Keywords: aryl halide amine amination coupling nickel catalyst regioselective chemoselective; C−N coupling; amination; anilines; aryl halides; nickel catalysis. We’ll tell you more about this compound (cas:4045-24-3).
An efficient and operationally simple Ni-catalyzed amination protocol has been developed. This methodol. features a simple NiII salt, an organic base and catalytic amounts of both a pyridinium additive and Zn metal. A diverse number of (hetero)aryl halides RX (R = 4-methanesulfonylphenyl, 3-cyanopyridin-2-yl, 1,3-benzoxazol-2-yl, etc.; X = Br, Cl) were coupled successfully with primary and secondary alkyl amines and anilines such as cyclohexanamine, pyrrolidine, 4-methylaniline, etc. in good to excellent yields RR1 [R1 = cyclohexylaminyl, pyrrolidin-1-yl, (4-methylphenyl)aminyl, etc.]. Similarly, benzophenone imine gave the corresponding N-arylation product N-(4-(methylsulfonyl)phenyl)-1,1-diphenylmethanimine in an excellent yield.
The article 《Nickel-Catalyzed Amination of (Hetero)aryl Halides Facilitated by a Catalytic Pyridinium Additive》 also mentions many details about this compound(4045-24-3)Recommanded Product: 4045-24-3, you can pay attention to it, because details determine success or failure
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem