One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Computed Properties of C5H9NO, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 5264-35-7, Name is 5-Methoxy-3,4-dihydro-2H-pyrrole, molecular formula is C5H9NO
Discovery of R-142086 as a factor Xa (FXa) inhibitor: Syntheses and structure-activity relationships of cinnamyl derivatives1,2
To develop a novel and effective anticoagulant with potent and selective factor Xa (FXa) inhibitory activity, a new series of cinnamyl derivatives with enhanced lipophilicity and prodrug forms were synthesized and their biological activities were evaluated. As a result, we found that cinnamyl derivative (N-{4-[1-(acetimidoyl)-piperidin-4-yloxy]-3-carbamoylphenyl}-N-[(Z) -3-(3-amidinophenyl)-2-fluoro-2-propenyl]sulfamoyl)acetic acid di-hydrochloride (26d, R-142086) with a fluorine atom on the double bond exhibited potent anticoagulant activity and no mutagenic potential. Moreover, orally administered R-142086 exhibited potent anti-FXa activity and anticoagulant activity in dogs.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Computed Properties of C5H9NO, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 5264-35-7, in my other articles.
Reference£º
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem