New discoveries in chemical research and development in 2021.In classical electrochemical theory, both the electron transfer rate and the adsorption of reactants at the electrode control the electrochemical reaction. In an article, author is Kuznecovs, Jevgenijs, once mentioned the application of 155899-66-4, Name is (3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol, molecular formula is C8H15NO3, molecular weight is 173.2096, MDL number is MFCD20527303, category is pyrrolines. Now introduce a scientific discovery about this category, COA of Formula: https://www.ambeed.com/products/155899-66-4.html.
Synthesis and study of new 5-substituted 1-acetyl-4-phenyl-3-pyrrolin-2-ones as potential antitumor agents
The treatment of 1-acetyl-5-bromo-4-phenyl-3-pyrrolin-2-one with appropriate silver salts in benzene promotes the substitution of bromine with chloride, fluoride, nitrite, nitrate, and thiocyanate groups. Biological testing of the newly synthesized compounds resulted in the discovery of moderate indoleamine 2,3-dioxygenase and matrix metalloproteinase inhibiting properties for NO2 and SCN derivatives in combination with low antitumor effect in vivo. However, testing of the NO2 derivative in mice with transplanted 4T1 mammary and CT-26 mouse colon carcinomas led to a considerable decrease in tumor volume and lung metastases without undesirable toxic effects evidencing potent tumor supressing properties.
Therefore, this conceptually novel strategy might open impressive avenues to establish green and sustainable chemistry platforms. 155899-66-4, you can contact me at any time and look forward to more communication. COA of Formula: https://www.ambeed.com/products/155899-66-4.html.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem