766-36-9, 3-Ethyl-4-methyl-2,5-dihydro-1H-pyrrol-2-one is a pyrrolines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,766-36-9
Compound 4 (0.30 g, 0.98 mmol) and 3-ethyl-4-methyl-1,5-dihydro-2H-pyrrol-2-one (0.14 g, 1.12 mmol) were dissolved in a mixture of 4 M KOH (12 mL) and methanol (7 mL) resulting in a yellow mixture. The reaction mixture was heated at reflux under N2 atmosphere for 24 h. After 24 h, the solution was cooled to rt then acidified with HCl (conc.) until red on pH paper, resulting in a yellow precipitate (0.27 g, 0.94 mmol, 96percent). Mp 345?351 ¡ãC. 1H NMR (400 MHz, DMSO, 30 ¡ãC) delta (ppm) 12.33 (s, 1H), 6.57(s, 1H), 2.59 (s, 3H), 2.31 (q, J=7.87 Hz, 2H), 2.13 (s, 3H), 1.04 (t, J=7.48 Hz, 3H); 13C NMR (100 MHz, DMSO, 30 ¡ãC): delta (ppm) 168.2, 162.7, 157.0, 141.9, 141.2, 137.6, 133.3, 128.2, 123.7, 116.1, 96.2, 16.6, 13.4, 11.4, 9.81; IR (ATR) (cm?1): 3330 (w), 3019 (w), 1732 (s), 1657 (s), 1525 (w), 1470 (m), 1292 (s), 1275 (s), 1185 (m), 1107 (m), 775 (m), 704 (m); HR-MS (ESI+) C15H14N2O4 calcd: 286.0954 amu; found 286.0950 amu.
As the paragraph descriping shows that 766-36-9 is playing an increasingly important role.
Reference£º
Article; Jarvis, Tia; Saint-Louis, Carl Jacky; Fisch, Alexander R.; Barnes, Korry L.; Dean, Dolan; Flores, Luis A.; Hunt, Thomas F.; Munro, Lyndsay; Simmons, Tyler J.; Catalano, Vincent J.; Zhu, Lei; Schrock, Alan K.; Huggins, Michael T.; Tetrahedron; vol. 74; 14; (2018); p. 1698 – 1704;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem