New research progress on 83411-71-6 in 2021. Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 83411-71-6, Name is Bis(2,4,4-trimethylpentyl)phosphinic acid, molecular formula is C16H35O2P, belongs to pyrrolines compound, is a common compound. In a patnet, author is Liu, Hui, once mentioned the new application about 83411-71-6, Category: pyrrolines.
Enantioselective dearomative [3+2] annulation of 5-amino-isoxazoles with quinone monoimines
The first enantioselective dearomative [3+2] annulation of 5-amino-isoxazoles with quinone monoimines was realized using a chiral phosphoric acid as catalyst. Various novel (bridged) isoxazoline fused dihydrobenzofurans bearing two continuous quaternary stereocenters were achieved in moderate to good yields (up to 94%) with moderate to good enantioselectivities (up to 98% ee). The absolute configurations of two products were assigned by X-ray crystal structural analyses and a plausible reaction mechanism was proposed.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 83411-71-6. Category: pyrrolines.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem