Chemical engineers work across a number of sectors, processes differ within each of these areas, but chemistry and chemical engineering roles are found throughout, and are directly involved in the process of chemical products and materials. 29968-78-3, Name is 4-Nitrophenylethylamine hydrochloride, molecular formula is , belongs to pyrrolines compound. In a document, author is Liu, Zhuqing, Reference of 29968-78-3.
Selective 1,4-Addition of Organolithiums to Maleate Monoesters with Application for a Short Efficient Route to Azaindanones
The ability of maleate half-ester salts to serve as electrophilic partners in 1,4-conjugate addition reactions with control of regioselectivity has previously been explored in only a limited context with soft nucleophiles. We have demonstrated that benzylic anions of picolines, as well as enolates of ketones, esters, and nitriles, react with lithium 4-( tert -butoxy)-4-oxobutenoate in a completely regioselective manner. This new method was applied to an expedient two-step process for preparing a key azaindanone intermediate for the clinical-candidate drug MK-8666.
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Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem