Chemical engineers ensure the efficiency and safety of chemical processes, adapt the chemical make-up of products to meet environmental or economic needs, and apply new technologies to improve existing processes. 67604-48-2, Name is 5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one, molecular formula is C15H12O5, belongs to pyrrolines compound, is a common compound. In a patnet, author is Sha, Qiang, once mentioned the new application about 67604-48-2, Synthetic Route of 67604-48-2.
Asymmetric synthesis of 1H-pyrrol-3(2H)-ones from 2,3-diketoesters by combination of aldol condensation with benzilic acid rearrangement
An efficient two-step protocol for the asymmetric synthesis of 1H-pyrrol-3(2H)-one derivatives in 99% ee from conveniently accessed 2,3-diketoesters has been developed.
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Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem