Name: 2-((4-Fluorophenyl)sulfonyl)hexahydropyrrolo[1,2-a]pyrazin-6(2H)-one, When developing chemical systems it’s of course important to gain a deep understanding of the chemical reaction process. 272786-64-8, Name is 2-((4-Fluorophenyl)sulfonyl)hexahydropyrrolo[1,2-a]pyrazin-6(2H)-one, SMILES is O=C1CCC2CN(S(=O)(C3=CC=C(F)C=C3)=O)CCN21, belongs to pyrrolines compound. In a article, author is Mattern, RH, introduce new discover of the category.
Synthesis of N-substituted pyrrolin-2-ones
During studies towards the synthesis of microcolin analogues, an unexpected dehydration was observed when 1-benzyloxycarbonyl-4-hydroxy-5-methylpyrrolidin-2-one was treated with di-tert-butyl dicarbonate in the presence of 4-dimethylaminopyridine. This reaction was used for the stereospecific synthesis of several N-protected pyrrolin-2-ones.
The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules. In my other articles, you can also check out more blogs about 272786-64-8. Name: 2-((4-Fluorophenyl)sulfonyl)hexahydropyrrolo[1,2-a]pyrazin-6(2H)-one.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem