Research speed reading in 2021. The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 556-50-3, Name is 2-(2-Aminoacetamido)acetic acid, molecular formula is C4H8N2O3. In an article, author is Green, MP,once mentioned of 556-50-3, Formula: https://www.ambeed.com/products/556-50-3.html.
An enantioselective formal synthesis of the proteasome inhibitor (+)-lactacystin
An enantioselective formal synthesis of the proteasome inhibitor (+)-lactacystim has been achieved using an alkylidene carbene 1,5-CH insertion reaction as a key step. The key cyclisation precursor was synthesised in high diastereomeric excess using a combination of known procedures, with the two key asymmetric centres being introduced via a Sharpless asymmetric epoxidation reaction. KHMDS induced 1,5-CH insertion produced a 3-pyrroline product, which was oxidised to the corresponding 3-pyrrolin-2-one using (1) TPAP/NMO; (2) NaCIO2; (3) NaBH4. The formal synthesis was then completed with a few standard functional group interconversions. (C) 2002 Published by Elsevier Science Ltd.
Formula: https://www.ambeed.com/products/556-50-3.html, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 556-50-3.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem