As a society publisher, everything we do is to support the scientific community – so you can trust us to always act in your best interests, and get your work the international recognition that it deserves. 578-95-0, Name is Acridin-9(10H)-one, molecular formula is C13H9NO, belongs to pyrrolines compound, is a common compound. In a patnet, author is Pal, M, once mentioned the new application about 578-95-0, Category: pyrrolines.
A rapid and direct access to symmetrical/unsymmetrical 3,4-diarylmaleimides and pyrrolin-2-ones
1.8-Diazabicyclo[5.4.0]undec-7ene (DBU) facilitated the oxidative cyclization of phenacyl amide in the presence of atmospheric oxygen under environmentally friendly conditions. The reaction has been studied under various conditions and a plausible mechanism is proposed. This ‘green’ reaction proceeds via intramolecular ring closure of the amide followed by subsequent reaction with molecular oxygen where DBU played a crucial role. A variety of phenacyl amides were treated with DBU in acetonitrile under an oxygen atmosphere to dive the symmetrical/unsymmetrical 3.4-diarylsubstituted maleimides in good yields. Corresponding pyrrolin-2-ones however, were obtained in good to excellent yields when K2CO3 was used in place of DBU affording a practical synthesis of these compounds of potential biological interest. (C) 2004 Elsevier Ltd. All rights reserved.
You can get involved in discussing the latest developments in this exciting area about 578-95-0. Category: pyrrolines.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem