Extracurricular laboratory: Synthetic route of 34941-92-9

I hope my short article helps more people learn about this compound(4-Chloro-2-fluoropyridine)HPLC of Formula: 34941-92-9. Apart from the compound(34941-92-9), you can read my other articles to know other related compounds.

HPLC of Formula: 34941-92-9. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 4-Chloro-2-fluoropyridine, is researched, Molecular C5H3ClFN, CAS is 34941-92-9, about Synthesis of N-alkylated 2-pyridones through Pummerer type reactions of activated sulfoxides and 2-fluoropyridine derivatives. Author is Hu, Gang; Xu, Jiaxi; Li, Pingfan.

N-Alkylated 2-pyridone products were obtained in good to excellent yields through a one-pot procedure involving either normal or interrupted Pummerer reactions between triflic anhydride activated sulfoxides and 2-fluoropyridine derivatives, followed by hydrolysis. This is a rare case that uses 2-fluoropyridine as a nucleophile in Pummerer type reactions.

I hope my short article helps more people learn about this compound(4-Chloro-2-fluoropyridine)HPLC of Formula: 34941-92-9. Apart from the compound(34941-92-9), you can read my other articles to know other related compounds.

Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem