In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called A Concise Stereoselective Total Synthesis of Methoxyl Citreochlorols and Their Structural Revisions, published in 2021-03-15, which mentions a compound: 58081-05-3, mainly applied to methoxyl citreochlorol stereoselective total synthesis; regioselective reduction iodo esterification chemoselective ring opening dichloromethylation, Product Details of 58081-05-3.
A concise, stereoselective and protecting group free approaches for the total synthesis of (-)-(2S,4R)- and (+)-(2R,4S)-3′-methoxyl citreochlorols, e.g., I, and their stereoisomers are demonstrated. All four stereoisomers were synthesized to establish the absolute stereochem. of the reported structures and the structures were revised accordingly. The approach involves chelation controlled regioselective reduction of a diester, silyl iodide promoted ring-opening iodo esterification of lactones, highly chemo- and regioselective ring-opening of an epoxy ester, dichloromethylation of a carboxyl group, and syn- and anti-selective reduction of the resulted β-hydroxy ketone as key steps.
I hope my short article helps more people learn about this compound((R)-4-Hydroxydihydrofuran-2(3H)-one)Product Details of 58081-05-3. Apart from the compound(58081-05-3), you can read my other articles to know other related compounds.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem