Formula: C4H6O3. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: (R)-4-Hydroxydihydrofuran-2(3H)-one, is researched, Molecular C4H6O3, CAS is 58081-05-3, about The semisynthetic spin-labelled derivatives of 3-hydroxybutanolide as potential oxidative stress inhibitors.
To obtain more accessible oxidative stress inhibitors, a series of novel spin-labeled derivatives of 3-hydroxybutanolide with the natural active compound (kinsenoside) as the lead compound were designed, synthesized from nitroxide free radical piperidines and pyrrolines and the main structural unit of kinsenoside: 3-hydroxybutanolide. Antioxidant activity screening of these derivatives was performed using MTT method on rat pheochromocytoma PC12 cells. The antioxidative stress effect was further investigated on the changes of the important antioxidant enzyme activities and intracellular reactive oxygen species production Some of the derivatives showed comparable or superior antioxidative stress activity to kinsenoside. Also, most of the tested derivatives displayed obvious antioxidative ability in concentrations Cytotoxic assay simultaneously indicated that all compounds had very low toxicity to normal cells. Based on the observed results, the structure-activity relationship of these derivatives was discussed.
In some applications, this compound(58081-05-3)Formula: C4H6O3 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem