In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Single-step conversion of chiral carnitine and derivatives into (S)- and (R)-β-substituted γ-butyrolactones, published in 1997-01-31, which mentions a compound: 58081-05-3, mainly applied to butyrolactone preparation; carnitine cyclocondensation, Safety of (R)-4-Hydroxydihydrofuran-2(3H)-one.
An efficient 1-step conversion of chiral carnitine and its derivatives into stereoisomerically pure (S)- and (R)-β-substituted γ-butyrolactones by cyclocondensation is described. (S)- or (R)-carnitine and (R)-aminocarnitine give β-hydroxy-γ-butyrolactone and β-amino-γ-butyrolactone in 82 and 77% yield, resp., with retention. (R)-(acetylamino)carnitine gives (R)-β-acetylamino-γ-butyrolactone in 90% yield, while (R)-acetylcarnitine gives 2(5H)-furanone under the same reaction conditions in 77% yield via cyclization and subsequent elimination. (R)-N-benzyloxycarnitinamide gives a mixture of pyrrolidinone (11% yield) and furanoyl imidate (50% yield) derivatives
There is still a lot of research devoted to this compound(SMILES:O=C1OC[C@H](O)C1)Safety of (R)-4-Hydroxydihydrofuran-2(3H)-one, and with the development of science, more effects of this compound(58081-05-3) can be discovered.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem