The important role of 34941-92-9

Here is just a brief introduction to this compound(34941-92-9)SDS of cas: 34941-92-9, more information about the compound(4-Chloro-2-fluoropyridine) is in the article, you can click the link below.

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Selective C-H Fluorination of Pyridines and Diazines Inspired by a Classic Amination Reaction, published in 2013-11-22, which mentions a compound: 34941-92-9, Name is 4-Chloro-2-fluoropyridine, Molecular C5H3ClFN, SDS of cas: 34941-92-9.

Fluorinated heterocycles are prevalent in pharmaceuticals, agrochems., and materials. However, reactions that incorporate fluorine into heteroarenes are limited in scope and can be hazardous. The authors present a broadly applicable and safe method for the site-selective fluorination of a single carbon-hydrogen bond in pyridines and diazines using com. available silver(II) fluoride. The reactions occur at ambient temperature within 1 h with exclusive selectivity for fluorination adjacent to nitrogen. The mild conditions allow access to fluorinated derivatives of medicinally important compounds, as well as a range of 2-substituted pyridines prepared by subsequent nucleophilic displacement of fluoride. Mechanistic studies demonstrate that the pathway of a classic pyridine amination can be adapted for selective fluorination of a broad range of nitrogen heterocycles.

Here is just a brief introduction to this compound(34941-92-9)SDS of cas: 34941-92-9, more information about the compound(4-Chloro-2-fluoropyridine) is in the article, you can click the link below.

Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem