Recommanded Product: 4045-24-3. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 4-Methoxypiperidine, is researched, Molecular C6H13NO, CAS is 4045-24-3, about Nonbisphosphonate inhibitors of Plasmodium falciparum FPPS/GGPPS. Author is Kabeche, Stephanie; Aida, Jumpei; Akther, Thamina; Ichikawa, Takashi; Ochida, Atsuko; Pulkoski-Gross, Michael J.; Smith, Mark; Humphries, Paul S.; Yeh, Ellen.
A series of novel thiazole-containing amides such as I.TFA were synthesized as inhibitors of Plasmodium falciparum farnesyldiphosphate synthase (PfFPPS) and geranylgeranyldiphosphate synthase (PfGGPPS). A structure-activity relationship study of these compounds led to the identification of potent and selective PfFPPS/GGPPS inhibitors with good in vitro ADME profiles. The most promising candidate mols. were progressed to mouse in vivo PK studies and demonstrated adequate free drug exposure to warrant further investigation.
In addition to the literature in the link below, there is a lot of literature about this compound(4-Methoxypiperidine)Recommanded Product: 4045-24-3, illustrating the importance and wide applicability of this compound(4045-24-3).
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem