Analyzing the synthesis route of 119020-01-8

119020-01-8, As the paragraph descriping shows that 119020-01-8 is playing an increasingly important role.

119020-01-8, (S)-1-Boc-2-(Aminomethyl)pyrrolidine is a pyrrolidine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: 6-(methoxycarbonyl)pyridine-2-carboxylic acid, 8 was dissolved in dichloromethane, 1 equivalent of corresponding amine (for 11a-c) or R-sulfamide (for 9a-c), EDCI, DMAP was added consecutively. The reaction mixture was stirred at room temperature for 72 h. After that the solution was washed with 10% HCl solution and distilled water, the organic layer was dried over anhydrous sodium sulphate and concentrated under reduced pressure to provide an orange red oil, the crude product was purified by flash chromatography through deactivated silica, eluting with 19:1 dichloromethane-methanol mixture. After evaporation of the solvents, the title product was obtained as white solid.

119020-01-8, As the paragraph descriping shows that 119020-01-8 is playing an increasingly important role.

Reference£º
Article; Wang, Lei; Tang, Ruiren; Yang, Hua; Journal of the Korean Chemical Society; vol. 57; 5; (2013); p. 591 – 598;,
Pyrrolidine – Wikipedia
Pyrrolidine | C4H9N – PubChem