The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Aliphatic and aromatic glucosides from Anoectochilus koshunensis》. Authors are Ito, Aiko; Kasai, Ryoji; Yamasaki, Kazuo; Sugimoto, Hiroyuki.The article about the compound:(R)-4-Hydroxydihydrofuran-2(3H)-onecas:58081-05-3,SMILESS:O=C1OC[C@H](O)C1).Synthetic Route of C4H6O3. Through the article, more information about this compound (cas:58081-05-3) is conveyed.
A new simple aliphatic glucoside, 3-(R)-3-β-D-glucopyranosyloxybutanolide (kinsenoside) with its congeners and a heterocyclic aromatic glucoside, β-glucopyranosyl-3-pyridinemethanol (nicoloside) were isolated from whole plants of A. koshunensis. Their structures were elucidated from chem. and spectroscopic evidence.
After consulting a lot of data, we found that this compound(58081-05-3)Synthetic Route of C4H6O3 can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem