So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Hu, Gang; Xu, Jiaxi; Li, Pingfan researched the compound: 4-Chloro-2-fluoropyridine( cas:34941-92-9 ).Application In Synthesis of 4-Chloro-2-fluoropyridine.They published the article 《Synthesis of N-alkylated 2-pyridones through Pummerer type reactions of activated sulfoxides and 2-fluoropyridine derivatives》 about this compound( cas:34941-92-9 ) in Organic & Biomolecular Chemistry. Keywords: pyridone alkylated preparation Pummerer sulfoxide fluoropyridine. We’ll tell you more about this compound (cas:34941-92-9).
N-Alkylated 2-pyridone products were obtained in good to excellent yields through a one-pot procedure involving either normal or interrupted Pummerer reactions between triflic anhydride activated sulfoxides and 2-fluoropyridine derivatives, followed by hydrolysis. This is a rare case that uses 2-fluoropyridine as a nucleophile in Pummerer type reactions.
After consulting a lot of data, we found that this compound(34941-92-9)Application In Synthesis of 4-Chloro-2-fluoropyridine can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem