Introduction of a new synthetic route about 58081-05-3

The article 《Total synthesis of (+)-phrymarolin I from (+)-malic acid》 also mentions many details about this compound(58081-05-3)Computed Properties of C4H6O3, you can pay attention to it, because details determine success or failure

Computed Properties of C4H6O3. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: (R)-4-Hydroxydihydrofuran-2(3H)-one, is researched, Molecular C4H6O3, CAS is 58081-05-3, about Total synthesis of (+)-phrymarolin I from (+)-malic acid. Author is Okazaki, Momotoshi; Ishibashi, Fumito; Shuto, Yoshihiro; Taniguchi, Eiji.

(+)-Phrymarolin I (I) was stereoselectively synthesized from (R)-(+)-3-hydroxybutanolide that had been prepared via regioselective reduction of (+)-malic acid or microbial reduction of 4-tert-butoxyacetoacetate. The procedure is more efficient than the previous synthesis in terms of fewer reaction steps and the easier availability of the starting material.

The article 《Total synthesis of (+)-phrymarolin I from (+)-malic acid》 also mentions many details about this compound(58081-05-3)Computed Properties of C4H6O3, you can pay attention to it, because details determine success or failure

Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem