5264-35-7, 5-Methoxy-3,4-dihydro-2H-pyrrole is a pyrrolines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,5264-35-7
To a solution of 5-methoxy-3,4-dihydro-2H-pyrrole (520mg) in MeOH (8 mL) was added (1 S)- 1 H-inden-1 -amine, 2,3-dihydro (538 mg, 4.04 mmol, CAS 61341 -86-4) at room temperature. The mixture was stirred at room temperature for 40 h. The reaction was then cooled to room temperature and concentrated. Flash column chromatography (5percent 7N NH3 in MeOH/DCM) yielded (S)-N-(2,3-dihydro-1 H-inden-1 -yl)-3,4-dihydro-2H- pyrrol-5-amine, as a white solid. 1H NMR (300MHz, CDCI3) delta: 7.30 – 7.39 (m, 5H), 7.13 – 7.28 (m, 3H), 5.25 – 5.38 (m, 1 H), 3.72 (t, J = 6.7 Hz, 2H), 2.91 – 3.04 (m, 1 H), 2.77 – 2.91 (m, 1 H), 2.54 – 2.72 (m, 1 H), 2.35 – 2.54 (m, 2H), 1.93 – 2.10 (m, 2H), 1.76 – 1.91 (m, 1H).
The synthetic route of 5264-35-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; ALLERGAN, INC.; CHOW, Ken; GIL, Daniel W.; DONELLO, John E.; WANG, Liming; CORPUZ, Evelyn G.; FANG, Wenkui K.; SINHA, Santosh C.; DIBAS, Mohammed I.; WO2011/44229; (2011); A1;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem