One of the major reasons is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time, to discover the sequence of events that occur at the molecular level. 17057-04-4, name is 4-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-benzoicacid, introduce a new downstream synthesis route., 17057-04-4
Derivative 1 was synthesized using a modified procedure reported by Willner etal. [51] as it is also described by Lau etal. [31]. A cooled suspension (0 C) of molecule 4 (211 mg, 0.97 mmol) in methylene chloride (4.5 mL) was treated with triethylamine (190 muL, 1.36 mmol) and isobutyl chloroformate (175 muL, 1.34 mmol). The mixture was stirred for 1 h at 0 C and at room temperature (22 C) for about 1 h. Afterwards, tert-butyl carbazate (128 mg, 0.97 mmol) dissolved in methylene chloride (0.8 mL) was added dropwise to the mixture and stirred for an additional 12 h at 22 C. The reaction mixture was diluted with ethyl acetate (55 mL) and methylene chloride (20 mL) and washed twice with saturated NaHCO3 (2 ¡Á 50 mL), twice with 0.1 N HCI (2 ¡Á 50 mL), twice with saturated NaCl (2 ¡Á 50 mL), and finally with H2O (50 mL). The organic phase was dried (MgSO4) and evaporated to give crude derivative 1. The product was purified by flash chromatography, using a mixture of hexanes/acetone (3/2), to yield 173 mg (54 %) of 1., 17057-04-4
This molecular description is the mechanism of the reaction; it describes how individual atoms, ions, or molecules interact to form particular products.If you are interested, you can also browse other articles of 17057-04-4. We look forward to the emergence of more reaction modes in the future.
Reference£º
Article; Hamelin-Morrissette, Jovane; Cloutier, Suzie; Girouard, Julie; Belgorosky, Denise; Eijan, Ana Maria; Legault, Jean; Reyes-Moreno, Carlos; Berube, Gervais; European Journal of Medicinal Chemistry; vol. 96; (2015); p. 259 – 268;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem