One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, 17057-04-4, such as the rate of change in the concentration of reactants or products with time.In a article, authors is Mohammed, Mohammed Khalaf, mentioned the application of 17057-04-4, Name is 4-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-benzoicacid, molecular formula is C11H7NO4
Synthesis, characterization and cytotoxicity appraisal of original 1, 2, 3-Triazole derivatives, against breast cancer cell lines (MDA-MB-231)
The present study established the efficient separate synthesis of four unique 1, 2, 3-triazole derivatives (M1, M2, M3, M4) via conducting 1,3-dipolar cycloaddition of N-((4-azidophenyl) sulfonyl) acetamide, with substituted N-phenylmaleimide. FTIR, 1H NMR, 13C NMR, and mass spectra were utilized for the characterization of the triazoles. The cytotoxic activities of these compounds, with regards to breast cancer cell lines (MDA-MB-231), were then evaluated. The cytotoxicity pre-screening outcomes for 100 muM portrayed a variety of actions, while the IC50 values with concentrations of 0-500 MuM for 48 hours, the results are 2.542, 2.929, 2.429, and 2.864 MuM for the compounds M1, M2, M3, and M4 respectively. Remarkably, the M2 and M4 para-substituted compounds exhibited superior IC50 values, in comparison to the M1 and M3 ortho-substituted compounds. This suggests that the M1 and M3 compounds have the potential to perform as against breast cancer.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. 17057-04-4, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 17057-04-4, in my other articles.
Reference£º
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem