Chemical engineers ensure the efficiency and safety of chemical processes, adapt the chemical make-up of products to meet environmental or economic needs, and apply new technologies to improve existing processes. 155899-66-4, Name is (3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol, molecular formula is C8H15NO3, belongs to pyrrolines compound, is a common compound. In a patnet, author is Kuznecovs, Jevgenijs, once mentioned the new application about 155899-66-4, HPLC of Formula: https://www.ambeed.com/products/155899-66-4.html.
Synthesis and study of new 5-substituted 1-acetyl-4-phenyl-3-pyrrolin-2-ones as potential antitumor agents
The treatment of 1-acetyl-5-bromo-4-phenyl-3-pyrrolin-2-one with appropriate silver salts in benzene promotes the substitution of bromine with chloride, fluoride, nitrite, nitrate, and thiocyanate groups. Biological testing of the newly synthesized compounds resulted in the discovery of moderate indoleamine 2,3-dioxygenase and matrix metalloproteinase inhibiting properties for NO2 and SCN derivatives in combination with low antitumor effect in vivo. However, testing of the NO2 derivative in mice with transplanted 4T1 mammary and CT-26 mouse colon carcinomas led to a considerable decrease in tumor volume and lung metastases without undesirable toxic effects evidencing potent tumor supressing properties.
Therefore, this conceptually novel strategy might open impressive avenues to establish green and sustainable chemistry platforms. 155899-66-4, you can contact me at any time and look forward to more communication. HPLC of Formula: https://www.ambeed.com/products/155899-66-4.html.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem