New learning discoveries about 199336-83-9

199336-83-9 (R)-1-Boc-3-(methylamino)pyrrolidine 45089543, apyrrolidine compound, is more and more widely used in various fields.

199336-83-9, (R)-1-Boc-3-(methylamino)pyrrolidine is a pyrrolidine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a solution of 2, 6-dichloronicotinonitrile (2.2 mmol) and DIPEA (10 mmol) in DMF (10 mL) was added (i?)-tert-butyl 3-(methylamino) pyrrolidine- 1-carboxylate with stirring at room temperature. The reaction mixture was stirred at 100 C overnight. Then the mixture was diluted with EtOAc, washed 3 times with water, dried, filtered and concentrated. The crude product was purified by flash chromatography to give the title compound., 199336-83-9

199336-83-9 (R)-1-Boc-3-(methylamino)pyrrolidine 45089543, apyrrolidine compound, is more and more widely used in various fields.

Reference£º
Patent; HUTCHISON MEDIPHARMA LIMITED; SU, Wei-Guo; DENG, Wei; LI, Jinshui; JI, Jianguo; WO2012/22265; (2012); A1;,
Pyrrolidine – Wikipedia
Pyrrolidine | C4H9N – PubChem