Category: 21724-96-9

Fun Route: New Discovery of 21724-96-9

This molecular description is the mechanism of the reaction; it describes how individual atoms, ions, or molecules interact to form particular products.If you are interested, you can also browse other articles of 21724-96-9. We look forward to the emergence of more reaction modes in the future.

One of the major reasons is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time, to discover the sequence of events that occur at the molecular level. 21724-96-9, name is 3-(4-Bromophenyl)-1H-pyrrole-2,5-dione, introduce a new downstream synthesis route., 21724-96-9

Preparation 2: (1/?,5S/1S,5/?)-1-(4-bromophenyl)-3-azabicyclo[3.1.0]hexane-2,4- dione (P2) Milled potassium hydroxide (6.29 g) was added in small portions to a stirred solution of trimethylsulfoxonium iodide (24.66 g) in anhydrous DMSO (224 mL). The resulting mixture was allowed to stir at room temperature for 1.5 h then 3-(4-bromophenyl)-1 H-pyrrole-2,5- dione (P1 , 14.12 g) dissolved in DMSO (90 mL) was then added dropwise and the resulting mixture was allowed to stir at room temperature for 20 minutes. Reaction temperature was brought to 0 ¡ãC and aqueous saturated NH4CI (150 mL) was slowly added, followed by Et2O (200 mL). After separation of the two phases, the aqueous layer was repeatedly extracted with Et2O (3 x 100 mL). Combined organic layers were washed with brine and then dried over Na2SO4. Evaporation of the solvent gave the crude title compound (9.61 g) which was used without further purification.MS (mlz): 265.1 [M-H]”., 21724-96-9

This molecular description is the mechanism of the reaction; it describes how individual atoms, ions, or molecules interact to form particular products.If you are interested, you can also browse other articles of 21724-96-9. We look forward to the emergence of more reaction modes in the future.

Reference£º
Patent; GLAXO GROUP LIMITED; WO2007/22935; (2007); A1;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

Analyzing the synthesis route of 21724-96-9

The synthetic route of 21724-96-9 has been constantly updated, and we look forward to future research findings.

21724-96-9, 3-(4-Bromophenyl)-1H-pyrrole-2,5-dione is a pyrrolines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Preparation 2: (1/?,5S/1S,5/?)-1-(4-bromophenyl)-3-azabicyclo[3.1.0]hexane-2,4- dione (P2) Milled potassium hydroxide (6.29 g) was added in small portions to a stirred solution of trimethylsulfoxonium iodide (24.66 g) in anhydrous DMSO (224 mL). The resulting mixture was allowed to stir at room temperature for 1.5 h then 3-(4-bromophenyl)-1 H-pyrrole-2,5- dione (P1 , 14.12 g) dissolved in DMSO (90 mL) was then added dropwise and the resulting mixture was allowed to stir at room temperature for 20 minutes. Reaction temperature was brought to 0 ¡ãC and aqueous saturated NH4CI (150 mL) was slowly added, followed by Et2O (200 mL). After separation of the two phases, the aqueous layer was repeatedly extracted with Et2O (3 x 100 mL). Combined organic layers were washed with brine and then dried over Na2SO4. Evaporation of the solvent gave the crude title compound (9.61 g) which was used without further purification.MS (mlz): 265.1 [M-H]”., 21724-96-9

The synthetic route of 21724-96-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; GLAXO GROUP LIMITED; WO2007/22935; (2007); A1;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem