Category: 57079-01-3

An elementary termolecular reaction involves the simultaneous collision of three atoms, molecules, or ions.57079-01-3, name is 11-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)undecanoic acid. Here is a downstream synthesis route of the compound 57079-01-3. 57079-01-3

57079-01-3, N-Maleimidyunndecanoic acid (171.4 g, 0.61 mol) and ethyl acetate (300 ml) were added to a 500 ml three-necked flaskand then thionyl chloride (142 g, 1.21 mol) A lot of gas released.After refluxing for 3h,almost no gas was released, the ethyl acetate was removed by concentration and excess thionyl chloride was added, and 200 ml of ethyl acetate was added to remove the residualacidonce toobtain crude N-maleimido undecanoyl chloride.The crude product was dissolved in 200 ml of ethyl acetate and added dropwise to a solution of N-hydroxysuccinimide (92 g, 0.8 mol) and diisopropylethylamine (129 g, 1.0 mol) in 300 ml of ethyl acetate. IceWater cooling control temperature does not exceed 20 , drip finished room temperature stirring 3h.The reaction mixture was washed with 200 ml of water to remove diisopropylethylamine hydrochloride, 100 ml of 1N hydrochloric acid to remove excess diisopropylethylamine, 200 ml of saturated saline, washed, dried and concentrated to give196 g of a white solid, ethyl acetate and petroleum Ether mixed solvent was recrystallized to give a white solid 152g,HPLC purity 98.2%, yield 66.1%.

There are, however, a few established termolecular elementary reactions. The reaction of nitric oxide with oxygen appears to involve termolecular steps. you can also browse my other articles about 57079-01-3

Reference£º
Patent; Suzhou Haofan Biological Technology Co., Ltd.; Lv Minjie; Zhang Haiyan; Wang Guichun; Sun Fangchao; (10 pag.)CN105037237; (2017); B;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

The molecularity of an elementary reaction is the number of molecules that collide during that step in the mechanism. If there is only a single reactant molecule in an elementary reaction, that step is designated as unimolecular.57079-01-3, name is 11-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)undecanoic acid. A new synthetic method of this compound is introduced below., 57079-01-3

A two-neck, 500 mL flask was charged with 26.24 g (0.1 mole) pentacyclopentadecane dimethanol, 9.04 g (0.105 mole) methacrylic acid, 29.54 g (0.105 mole) maleimidoundecanoic acid, 150 mL toluene, 2.0 g methanesulfonic acid, and 60 mg hydroquinone. A magnetic stir bar was placed in the flask and a gas inlet tube, Dean-Stark trap and condenser were attached. The mix was refluxed under an air sparge for 3.5 hours and 3.7 mL water (3.6 mL theoretical yield) was collected in the trap. The mixture was cooled to room temperature and neutralized with a mix of 15 g sodium bicarbonate and 5 mL water. The mix was dried with 12 g anhydrous magnesium sulfate and then passed over 20 g of silica gel. The bulk of the toluene was removed under vacuum on a rotary evaporator. The last trace of solvent was removed using an air sparge. The final product was a viscous, clear, red liquid that had a 40 C. viscosity of 3,028 centipoise. The product weighed 55.12 g (92.8% of theoretical yield). Thermogravimetric analysis (TGA) was performed on the compound (ramp rate of 10 C. per minute in air) and the retained weight was 100.0% and 99.9% at 200 C. and 300 C., respectively. The decomposition onset was 432.8 C. An FTIR was run on this compound and significant absorptions were found at 2925, 1714, 1638, 1407, 1172, 827, and 695 wavenumbers.

Thank you very much for taking the time to read this article. If you are also interested in other aspects of 57079-01-3, you can also browse my other articles.

Reference£º
Patent; Designer Molecules, Inc.; US8039663; (2011); B2;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

57079-01-3, The molecularity of an elementary reaction is the number of molecules that collide during that step in the mechanism. If there is only a single reactant molecule in an elementary reaction, that step is designated as unimolecular.57079-01-3, name is 11-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)undecanoic acid. A new synthetic method of this compound is introduced below.

57079-01-3, S1, 28.1 g of undecylmaleimido-11-acid is added to 120 ml of thionyl chloride,The reaction solution was heated to reflux for 3 h until the bubbler had no gas, and the reaction was stopped.The reaction solution was concentrated to dryness.Obtaining a yellow solid without post-treatment, directly proceeding to the next reaction;

A chemical reaction often occurs in steps, although it may not always be obvious to an observer. Thank you very much for taking the time to read this article. If you are also interested in other aspects of 57079-01-3, you can also browse my other articles.

Reference£º
Patent; Suzhou Haofan Biological Co., Ltd.; Lv Minjie; Wang Guichun; Liu Min; (14 pag.)CN109535058; (2019); A;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

57079-01-3,57079-01-3, 11-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)undecanoic acid is a pyrrolines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A two-neck, 500 mL flask was charged with 26.24 g (0.1 mole) pentacyclopentadecane dimethanol, 9.04 g (0.105 mole) methacrylic acid, 29.54 g (0.105 mole) maleimidoundecanoic acid, 150 mL toluene, 2.0 g methanesulfonic acid, and 60 mg hydroquinone. A magnetic stir bar was placed in the flask and a gas inlet tube, Dean-Stark trap and condenser were attached. The mix was refluxed under an air sparge for 3.5 hours and 3.7 mL water (3.6 mL theoretical yield) was collected in the trap. The mixture was cooled to room temperature and neutralized with a mix of 15 g sodium bicarbonate and 5 mL water. The mix was dried with 12 g anhydrous magnesium sulfate and then passed over 20 g of silica gel. The bulk of the toluene was removed under vacuum on a rotary evaporator. The last trace of solvent was removed using an air sparge. The final product was a viscous, clear, red liquid that had a 40 C. viscosity of 3,028 centipoise. The product weighed 55.12 g (92.8% of theoretical yield). Thermogravimetric analysis (TGA) was performed on the compound (ramp rate of 10 C. per minute in air) and the retained weight was 100.0% and 99.9% at 200 C. and 300 C., respectively. The decomposition onset was 432.8 C. An FTIR was run on this compound and significant absorptions were found at 2925, 1714, 1638, 1407, 1172, 827, and 695 wavenumbers.

57079-01-3 11-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)undecanoic acid 4618600, apyrrolines compound, is more and more widely used in various fields.

Reference£º
Patent; Designer Molecules, Inc.; US8039663; (2011); B2;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.57079-01-3,11-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)undecanoic acid,as a common compound, the synthetic route is as follows.

57079-01-3, S1, 28.1 g of undecylmaleimido-11-acid is added to 120 ml of thionyl chloride,The reaction solution was heated to reflux for 3 h until the bubbler had no gas, and the reaction was stopped.The reaction solution was concentrated to dryness.Obtaining a yellow solid without post-treatment, directly proceeding to the next reaction;

The synthetic route of 57079-01-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Suzhou Haofan Biological Co., Ltd.; Lv Minjie; Wang Guichun; Liu Min; (14 pag.)CN109535058; (2019); A;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.57079-01-3,11-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)undecanoic acid,as a common compound, the synthetic route is as follows.,57079-01-3

Example L1a 11-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-undecanoyl chloride 2.0 g (7.11 mmol) of 11-(2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-undecanoic acid is mixed with 15.5 ml of thionyl chloride and refluxed for 15 minutes. After cooling, it is mixed with toluene and evaporated to the dry state. 2.13 g (max. 7.11 mmol) of the title compound, which is further reacted without purification, is isolated.

57079-01-3 11-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)undecanoic acid 4618600, apyrrolines compound, is more and more widely used in various fields.

Reference£º
Patent; Klar, Ulrich; Willuda, Joerg; Menrad, Andreas; Bosslet, Klaus; US2005/234247; (2005); A1;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem