Modeling chemical reactions helps engineers virtually understand the chemistry, optimal size and design of the system, and how it interacts with other physics that may come into play. 129946-88-9, Name is 5-(Trifluoromethyl)-5H-dibenzo[b,d]thiophen-5-ium trifluoromethanesulfonate, molecular formula is , belongs to pyrrolines compound. In a document, author is Huo, Hao-Hua, Computed Properties of https://www.ambeed.com/products/129946-88-9.html.
Enantioselective Total Syntheses of (-)-FR901483 and (+)-8-epi-FR901483
The enantioselective total syntheses of the potent immunosuppressant FR901483 (1) and its 8-epimer (47) have been accomplished. Our approach features the use of building block 6 as the chiron, the application of the one-pot amide reductive bis-alkylation method to construct the chiral aza-quaternary center (dr = 9:1), regio- and diaster-eoselective intramolecular aldol reaction to build the bridged ring, and RCM to form the 3-pyrrolin-2-one ring.
Future efforts will undeniably focus on the diversification of the new catalytic transformations. These may comprise an expansion of the substrate scope from aromatic and heteroaromatic compounds to other hydrocarbons. Keep reading other articles of 129946-88-9. Computed Properties of https://www.ambeed.com/products/129946-88-9.html.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem